Custom Peptides
Cayman Chemical Aurantioobtusin, Purity: ≥95%, CAS: 67979-25-3, 10 mg
An anthraquinone with diverse biological activities; inhibits RLAR in vitro (IC50 = 13.6 μM); activates the AhR at 10 and 100 μM; inhibits arachidonic acid-, ADP-, and collagen-induced rat platelet aggregation; induces vasorelaxation in isolated precontracted rat mesenteric artery rings
Cayman Chemical Hypocrellin B, Purity: ≥98%, CAS: 123940-54-5, 10 mg
A fungal metabolite; decreases the viability of, and induces apoptosis in, MDA-MB-231 breast cancer cells when used in the presence of ultrasound exposure; increases the production of ROS in MDA-MB-231 cells at 2.5 µM with concomitant ultrasound exposure; active against MRSA at 20 µM in combination with ultrasound sonication
Cayman Chemical SEL120-34A (hydrochloride), Purity: ≥98%, CAS: 1609452-30-3, 10 mg
A dual inhibitor of Cdk8 and Cdk19 (IC50s = 4.4 and 10.4 nM, respectively); selective for Cdk8 and Cdk19 over a panel of CDK/cyclin complexes at 1 µM; inhibits IFN-γ-induced phosphorylation of STAT1 in HCT116 colon cancer cells at 0.1-5 µM; inhibits proliferation of MOLM-16, MV4-11, and KG-1 cells (GI50s = <1 µM); reduces tumor growth in a KG-1 mouse xenograft model at 60 mg/kg
Cayman Chemical Acetaminophen Glucuronide (sodium salt), Purity: ≥98%, CAS: 120595-80-4, 10 mg
An inactive metabolite of acetaminophen; formed via glucuronidation of acetaminophen by UGT1A6, UGT1A9, UGT1A1, and UGT2B15
Cayman Chemical Dipsacoside B, Purity: ≥95%, CAS: 33289-85-9, 10 mg
A triterpenoid saponin with hepatoprotective activity; enhances acetaminophen-induced autophagy and inhibits acetaminophen-induced apoptosis in HepG2 cells at 0.5 µM; increases survival in a mouse model of acetaminophen-induced acute liver failure at 50 mg/kg
Cayman Chemical 16-Epiestriol, Purity: ≥90%, CAS: 547-81-9, 10 mg
A metabolite of estrone; inhibits the growth of carbapenem-resistant A. baumannii at 200 µg/ml; inhibits carrageenan-induced paw edema in rats at 20 mg/kg; does not increase plasma or liver glucose levels in adrenalectomized rats at 240 µg/animal
Cayman Chemical Prohexadione, Purity: ≥98%, CAS: 88805-35-0, 10 mg
A plant growth regulator; inhibits the gibberellin plant hormone biosynthesis enzyme 3β-hydroxylase at 0.1, 1, and 10 mM; reduces the shoot length of peanut plants when applied at 0.5, 1.5, and 4.5 kg/hectare; inhibits JMJD2A demethylase at 1 mM; induces the differentiation of mouse neurospheres into neurons at 1, 1.5, and 2 mM
Cayman Chemical Benzoylmesaconine, Purity: ≥98%, CAS: 63238-67-5, 10 mg
An alkaloid; promotes isolated rat liver mitochondrial energy metabolism (EC50 = 30.95 µg/ml); increases survival in a mouse model of burn-associated HSV1 infection at 1 µg/kg; increases the latency to tail withdrawal or a struggling response in a tail pressure test in mice (ED50 = 38.9 mg/kg)
Cayman Chemical Rebaudioside M, Purity: ≥95%, CAS: 1220616-44-3, 10 mg
A natural non-caloric sweetener and TAS1R2/TAS1R3 agonist; increases intracellular calcium levels in HEK293 cells expressing human TAS1R2 and TAS1R3 (EC50 = 29.54 µM); has a relative sweetness potency 200-350 times that of sucrose; metabolized by gut microbiota to steviol
Cayman Chemical (S)-Tipifarnib, Purity: ≥98%, CAS: 192185-71-0, 10 mg
An inactive enantiomer of tipifarnib
Cayman Chemical N-desmethyl Asenapine, Purity: ≥98%, CAS: 128915-56-0, 10 mg
A metabolite of asenapine
Cayman Chemical (±)-Tuberonic Acid, Purity: ≥70%, CAS: 221682-86-6, 10 mg
A derivative of jasmonic acid
Cayman Chemical Hinokiflavone, Purity: ≥95%, CAS: 19202-36-9, 10 mg
A biflavonoid with diverse biological activities; inhibits the aggregation of Aβ40 in vitro (IC50 = 9.5 μM); promotes pre-mRNA splicing of the genes encoding Mcl-1 and eIF4α and inhibits pre-mRNA splicing of the genes encoding Hsp40 and RIOK3 in NB4 cells at 10 µM; increases protein SUMOylation in HEK293 cells at 10 µM; reduces the cytopathic effect of the influenza A subtypes H1N1 and H1N3, influenza B, parainfluenza type 3, and RSV (IC50s = 1.4, 1.3, 1.2, 1, and 2.5 µg/ml, respectively); inhibits the migration and invasion of, and induces apoptosis in, KYSE-150 cells from 10-40 µM; reduces tumor volume in a KYSE-150 mouse xenograft model at 25 or 50 mg/kg
Cayman Chemical Desthiazolylmethyl Ritonavir, Purity: ≥90%, CAS: 256328-82-2, 10 mg
A ritonavir degradation product